Infertility and assisted reproductive technologies — practice questions

Question 1 · difficulty L2 · understanding

What is the basic feature of in vitro fertilisation?

• A. Fertilisation occurs outside the body
• B. Fertilisation occurs only in the uterus
• C. Only sperm are cultured outside the body
• D. The embryo develops to birth entirely outside the body

Question 2 · difficulty L3 · understanding

Choose the correct statement regarding GIFT to overcome infertility.

• A. Ova collected from a female donor are transferred to the uterus of an infertile female.
• B. Early embryos with up to 8 blastomeres are transferred to the uterus of an infertile female.
• C. Early embryos with up to 8 blastomeres are transferred into the fallopian tube of an infertile female.
• D. It is the transfer of an ovum collected from a donor into the fallopian tube of another female who cannot

Question 3 · difficulty L3 · understanding

What are the potential drawbacks in adoption of the IVF method? A. High fatality risk to mother B. Expensive instruments and reagents C. Husband/wife necessary for being donors D. Less adoption of orphans E. Not available in India F. Possibility that the early embryo does not survive Choose the correct answer from the options given below:

• A. A, B, C, D only
• B. A, B, C, E, F only
• C. B, D, F only
• D. A, C, D, F only

Question 4 · difficulty L3 · understanding

Given below are two statements : Statement I :- Intra Cytoplasmic Sperm Injection (ICSI) is another specialised procedure of in-vivo fertilisation. Statement II :- Infertility cases due to inability of the male partner to inseminate female can be corrected by artificial insemination (AI). In the light of the above statements, choose the correct answer from the options given below:

• A. Statement I is correct but statement II is false
• B. Statement I is incorrect but Statement II is true
• C. Both Statement I and Statement II are true
• D. Both Statement I and Statement II are false.

Question 5 · difficulty L3 · understanding

In which of the following techniques, the embryos are transferred to assist those females who cannot conceive?

• A. GIFT and ICSI
• B. ZIFT and IUT
• C. GIFT and ZIFT
• D. ICSI and ZIFT

Question 6 · difficulty L3 · application

In ZIFT, what is transferred into the fallopian tube?

• A. A late embryo with more than eight blastomeres into the uterus
• B. A zygote or early embryo with up to about eight blastomeres
• C. Only unfertilised sperm
• D. A mature placenta

Question 7 · difficulty L3 · application

When is intracytoplasmic sperm injection especially useful?

• A. When ordinary fertilisation occurs easily without laboratory assistance
• B. When ovulation must be permanently stopped
• C. When one sperm must be injected directly into an ovum
• D. When only contraception is required

Question 8 · difficulty L5 · analysis

A woman produces normal ova but cannot retain an embryo in her oviduct because both tubes are blocked. Fertilisation is achieved in vitro and a later-stage embryo is available. Where should it generally be transferred?

• A. Into the cervix only
• B. Into a blocked fallopian tube
• C. Into the ovary
• D. Into the uterus