Which experiment proved DNA is the genetic material — practice questions

Question 1 · difficulty L1 · recall

The experiment demonstrating transformation in pneumococcus:

• A. Morgan cross
• B. Griffith experiment
• C. Miller experiment
• D. Meselson-Stahl experiment

Question 2 · difficulty L1 · recall

The experiment using bacteriophages to support DNA as genetic material:

• A. Griffith experiment
• B. Beadle-Tatum experiment
• C. Miller experiment
• D. Hershey-Chase experiment

Question 3 · difficulty L1 · recall

The scientists who identified DNA as the transforming principle using purified components:

• A. Jacob and Monod
• B. Meselson and Stahl
• C. Avery, MacLeod and McCarty
• D. Watson and Crick

Question 4 · difficulty L2 · understanding

In the Hershey-Chase experiment, which result supported DNA as the genetic material of bacteriophages?

• A. Phosphorus-labelled DNA entered bacteria
• B. Sulfur-labelled protein entered bacteria while phosphorus remained outside
• C. Neither isotope entered bacterial cells
• D. Both isotopes entered cells equally

Question 5 · difficulty L2 · understanding

Match List-I with List-II List - I List - II A Alfred Hershey and Martha Chase I Streptococcus pneumoniae B Euchromatin II Densely packed and dark-stained C Frederick Griffith III Loosely packed and light-stained D Heterochromatin IV DNA as genetic material confirmation Choose the correct answer from the options given below:

• A. A-IV, B-III, C-I, D-II
• B. A-III, B-II, C-IV, D-I
• C. A-II, B-IV, C-I, D-III
• D. A-IV, B-II, C-I, D-III

Question 6 · difficulty L3 · application

Heat-killed virulent bacteria transform live non-virulent bacteria, but transformation stops after DNase treatment. What does this indicate?

• A. Heat alone creates virulence
• B. Protein is the transforming principle
• C. RNA is always the only genetic material
• D. DNA is the transforming principle

Question 7 · difficulty L3 · understanding

Match List I with List II List - I List - II A. Frederick Griffith I. Genetic code B. Francois Jacob & Jacque Monod II. Semi-conservative mode of DNA replication C. Har Gobind Khorana III. Tranformation D. Meselson & Stahl IV. Lac operon Choose the correct answer from the options given below:

• A. A-III, B-II, C-I, D-IV
• B. A-III, B-IV, C-I, D-II
• C. A-II, B-III, C-IV, D-I
• D. A-IV, B-II, C-II, D-III

Question 8 · difficulty L3 · understanding

Which scientist conducted an experiment with 32 P and 35 S labelled phages for demonstrating that DNA is the genetic material?

• A. james D. Watson and F.H. C. Crick
• B. A. D Hershey and M.J. Chase
• C. F. Griffith
• D. O.T. Avery, C.M. MacLeod and M. McCarty

Question 9 · difficulty L3 · understanding

With reference to Hershey and Chase experiments. Select the correct statements. (A) Viruses grown in the presence of radioactive phosphorus contained radioactive DNA. (B) Viruses grown on radioactive sulphur contained radioactive proteins. (C) Viruses grown on radioactive phosphorus contained radioactive protein. (D) Viruses grown on radioactive sulphur contained radioactive DNA. (E) Viruses grown on radioactive protein contained radioactive DNA. Choose the most appropriate answer from the options given below :

• A. (D) and (E) only
• B. (A) and (B) only
• C. (A) and (C) only
• D. (B) and (D) only

Question 10 · difficulty L3 · understanding

Unequivocal proof that DNA is the genetic material was first proposed by

• A. Alfred Hershey and Martha Chase
• B. Avery, Macleoid and McCarthy
• C. Wilkins and Franklin
• D. Frederick Griffith