Transgenic animals — practice questions

Question 1 · difficulty L1 · recall

What is a transgenic animal?

• A. An animal with no DNA
• B. Any animal produced by selective breeding
• C. An animal engineered to carry a foreign gene
• D. Any cloned animal regardless of its genes

Question 2 · difficulty L2 · understanding

Why are transgenic animals useful for studying gene function?

• A. They cannot pass genes to offspring
• B. They eliminate the need for controls
• C. Every inserted gene produces the same phenotype
• D. Gene changes can reveal effects on physiology

Question 3 · difficulty L3 · understanding

The human protein named $\boldsymbol{\alpha}$-1-antitrypsin, obtained from transgenic animals, is used for the treatment of $\_\_\_\_$ .

• A. Emphysema
• B. Alzheimer's disease
• C. Rheumatoid arthritis
• D. Cystic fibrosis

Question 4 · difficulty L3 · understanding

Milk of transgenic ‘Cow Rosie’ was nutritionally more balanced product for human babies than natural cow milk because it contained:

• A. Human enzyme Adenosine Deaminase (ADA)
• B. Human protein $$\alpha$$-1-antitrypsin
• C. Human alpha-lactalbumin
• D. Human insulin-like growth factor

Question 5 · difficulty L3 · application

A transgenic mouse develops symptoms similar to a human genetic disease. What is a major research use of this model?

• A. Study disease mechanisms and potential treatments
• B. Replacing every human clinical study
• C. Producing methane
• D. Measure population allele frequencies across multiple human generations

Question 6 · difficulty L4 · analysis

Why might a transgenic animal be engineered to produce a human therapeutic protein in its milk?

• A. The protein automatically changes the animal into a human
• B. Milk can provide the therapeutic protein
• C. Milk prevents gene expression
• D. The animal no longer needs the inserted gene

Question 7 · difficulty L5 · analysis

A transgenic animal produces a therapeutic protein, but the protein is structurally altered by incorrect processing. What is the main concern?

• A. The gene can no longer be inherited
• B. The animal must lose all chromosomes
• C. Its activity or safety may be unsuitable
• D. Every transgenic protein is automatically safe